Extreme hypereosinophilia in sclerosing cholangitis
نویسندگان
چکیده
منابع مشابه
Sclerosing Cholangitis
INTRODUCTION Sclerosing cholangitis represents an array of chronic, cholestatic diseases of the intrahepatic and extrahepatic bile duct systems. Clinically, this syndrome is characterized by progressive fatigue, pruritus, and in later stages, by abdominal pain, recurrent fever, and jaundice. These symptoms are resultant from inflammatory and fibrosing obstruction of the biliary system. The prog...
متن کاملPrimary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disorder of the biliary system that results in progressive fibrosis and strictures of the intrahepatic and extrahepatic bile ducts. Typical radiological changes on retrograde cholangiography are shown in Figure 1. These strictures cause cholestatic liver disease that may progress to end-stage cirrhosis. The disorder has a strong ass...
متن کاملPrimary Sclerosing Cholangitis: Introduction
The prevalence of primary sclerosing cholangitis in the United States is approximately 1–6 cases per 100,000 population. Most patients with primary sclerosing cholangitis are men (75%) with an average age of approximately 40 years at diagnosis. The overwhelming majority of patients affected with primary sclerosing cholangitis are Caucasian. The etiology is unknown but current opinion favors an ...
متن کاملControversies in Primary Sclerosing Cholangitis
• MRCP should be used as the initial investigation to diagnose PSC as it has similar accuracy without the invasiveness of ERCP. • Patients with a high clinical suspicion of PSC but with normal cholangiogram should undergo liver biopsy to exclude small duct PSC. Likewise, liver biopsy is indicated if an overlap with autoimmune hepatitis is suspected. In this case, treatment with corticosteroids ...
متن کاملPregnancy in primary sclerosing cholangitis.
BACKGROUND There is a paucity of data on fertility or pregnancy in patients with primary sclerosing cholangitis (PSC). OBJECTIVE To assess fertility in PSC by comparing the number of children in a large cohort of PSC patients to healthy controls and to investigate the outcome of pregnancy, as well as the influence of pregnancy on the disease course. DESIGN Case series. SETTING Germany. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Internal Medicine Journal
سال: 2003
ISSN: 1444-0903
DOI: 10.1046/j.1445-5994.2003.00363.x